Support in osteoarthritis symptoms relief by Sizarol™

Support in alleviating the symptoms of osteoarthritis in dogs, cats and horses with specially selected ingredients in Sizarol™ products

Osteoarthritis, also known as osteoarthritis, is one of the most common conditions affecting dogs, cats, and horses. This condition leads to the gradual wear and tear of the articular cartilage, which causes pain, stiffness and limited mobility. The symptoms of this disease can significantly reduce the quality of life of our pets, which is why it is so important to find effective support methods. Sizarol products, thanks to their carefully selected ingredients, offer support in alleviating these symptoms.

Natural ingredients to support joint health

Sizarol™ products contain natural ingredients known for their anti-inflammatory and therapeutic properties. Here are some of the key ingredients that make our formulations so effective:

Glucosamine and Chondroitin

Sizarol™ products contain natural ingredients known for their anti-inflammatory and therapeutic properties. Here are some of the key ingredients that make our formulations so effective:

Glucosamine and Chondroitin

These two components are the basic building blocks of joint cartilage. They help to rebuild damaged cartilage, providing better cushioning of the joints, which reduces pain and improves their function.2,3

MSM (Methylsulfonylmethane)

MSM is known for its powerful anti-inflammatory properties. It helps reduce the pain and swelling associated with osteoarthritis.4

Hyaluronic Acid

This natural compound helps to moisturize the joints, which increases their elasticity and reduces friction. This makes the movement less painful and smoother.5

Multimodal treatment of osteoarthritis

An approach to treating osteoarthritis in animals may be most effective when it is multimodal. As Millward points out in the publication “Multimodal Management of Canine Osteoarthritis”1, the combination of various therapeutic methods brings the best results. Multimodal treatment may include:

  • Pharmacotherapy: The use of anti-inflammatory and analgesic drugs.
  • Supplementation: Regular administration of dietary supplements, such as those contained in Sizarol products, to support joint health.
  • Physiotherapy: Exercises, massages and physiotherapy treatments to help maintain joint mobility and reduce pain.
  • Weight Management: Maintaining an adequate body weight to reduce the strain on your joints.
  • Nutritional Modifications: A diet rich in nutrients to support joint health.

How do Sizarol™ products help your pets?

Sizarol™ products are designed to support the joint health of your pets. Regular use of our preparations can help with:

  • Pain Reduction: Thanks to the anti-inflammatory properties of our ingredients, Sizarol products help reduce the pain associated with osteoarthritis.
  • Improved Joint Mobility: Ingredients such as glucosamine and chondroitin support the restoration of cartilage, which improves joint mobility.
  • Strengthen Joints: Hyaluronic acid and MSM help to strengthen the structure of joints, which prevents further damage and supports their health in the long run.
  • Increased Living Comfort: Less pain and better joint mobility translate into a more comfortable life for your pets and allow them to enjoy their daily activities.
  1. Murray CJ, , Memish ZA. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012 Dec 15;380(9859):2197-223
  2. Felson DT. Clinical practice. Osteoarthritis of the knee. N Engl J Med. 2006 Feb 23;354(8):841-8. doi: 10.1056/NEJMcp051726. Erratum in: N Engl J Med. 2006 Jun 8;354(23):2520.
  3. Balazs EA, Watson D, Duff IF, Roseman S. Hyaluronic acid in synovial fluid. I. Molecular parameters of hyaluronic acid in normal and arthritis human fluids. Arthritis Rheum. 1967 Aug;10(4):357-76.
  4. Creamer P, Sharif M, George E, Meadows K, Cushnaghan J, Shinmei M, Dieppe P. Intra-articular hyaluronic acid in osteoarthritis of the knee: an investigation into mechanisms of action. Osteoarthritis Cartilage. 1994 Jun;2(2):133-40.
  5. Smith MM, Ghosh P. The synthesis of hyaluronic acid by human synovial fibroblasts is influenced by the nature of the hyaluronate in the extracellular environment. Rheumatol Int. 1987;7(3):113-22.
  6. Chow G, Nietfeld JJ, Knudson CB, Knudson W. Antisense inhibition of chondrocyte CD44 expression leading to cartilage chondrolysis. Arthritis Rheum. 1998 Aug;41(8):1411-9.
  7. Pozo MA, Balazs EA, Belmonte C. Reduction of sensory responses to passive movements of inflamed knee joints by hylan, a hyaluronan derivative. Exp Brain Res. 1997 Aug;116(1):3-9.
  8. Takahashi K, Goomer RS, Harwood F, Kubo T, Hirasawa Y, Amiel D. The effects of hyaluronan on matrix metalloproteinase-3 (MMP-3), interleukin-1beta(IL-1beta), and tissue inhibitor of metalloproteinase-1 (TIMP-1) gene expression during the development of osteoarthritis. Osteoarthritis Cartilage. 1999 Mar;7(2):182-90.
  9. Gomis A, Pawlak M, Balazs EA, Schmidt RF, Belmonte C. Effects of different molecular weight elastoviscous hyaluronan solutions on articular nociceptive afferents. Arthritis Rheum. 2004 Jan;50(1):314-26.
  10. Gotoh S, Onaya J, Abe M, Miyazaki K, Hamai A, Horie K, Tokuyasu K. Effects of the molecular weight of hyaluronic acid and its action mechanisms on experimental joint pain in rats. Ann Rheum Dis. 1993 Nov;52(11):817-22.
  11. Altman RD, Bedi A, Karlsson J, Sancheti P, Schemitsch E. Product Differences in Intra-articular Hyaluronic Acids for Osteoarthritis of the Knee. Am J Sports Med. 2016;44(8):2158-2165. doi:10.1177/0363546515609599